Dr. Min YE
Min YE, Ph. D.
Associate Professor of Pharmacognosy
Tel./fax: 010-82802024
Email: yemin@bjmu.edu.cn
EDUCATION & PROFESSIONAL EXPERIENCE
|
1975.11 |
Born in Huanggang, Hubei Province |
|
1997.7 |
B.Sc. |
Chinese Materia Medica, Beijing University of Chinese Medicine |
|
2000.7 |
M.Sc. |
Chinese Materia Medica, Beijing University of Chinese Medicine |
|
2003.7 |
Ph.D. |
Pharmacognosy, Peking University |
|
2003.7-2005.5 |
Postdoctoral Fellow
School of Pharmaceutical Sciences, Peking University |
|
2005.5-2006.1 |
Postdoctoral Fellow
Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, USA |
|
2006.1-2007.12 |
Postdoctoral Research Associate
Department of Pharmacology, School of Medicine, Yale University, New Haven, CT, USA |
|
2007.12-present |
Associate Professor
School of Pharmaceutical Sciences, Peking University |
RESEARCH INTERESTS
1. Chemical analysis and metabolism of traditional Chinese medicines
(1) Chemistry, quality control and LC/MS analysis of Chinese herbal medicines.
(2) Metabolism and pharmacokinetics (DMPK) of traditional Chinese medicines.
(3) Mass spectrometry of naturally occurred chemicals.
2. Biotransformation of bioactive natural products
(1) Biosynthesis of novel natural product derivates using microbial and plant cell cultures.
(2) Structure-activity relationship of bioactive natural products.
HONORS
1. Award (first class) from Ministry of Education, China, 2005 (third awardee).
2. Award (first class) from Ministry of Education, China, 2007 (second awardee).
3. Teaching Award (third class) for young teachers, Peking University, 2008.
4. Elected into Beijing NOVA program, 2009.
SELECTED PUBLICATIONS
1. Cheng Xiang, Xue Qiao, Qing Wang, Rui Li, Wenjuan Miao, Dean Guo, Min Ye*. From single compounds to herbal extract: a strategy to systematically characterize the metabolites of licorice in rats. Drug Metab. Dispos. 2011, 39(9), 1597-1608.
2. Yonghong Liang, Min Ye*, Wenzhi Yang, Xue Qiao, Haijun Yang, Xiaoli Wang, Dean Guo*. Flavan-3-ols from the rhizomes of Drynaria fortunei. Phytochemistry 2011, 72(14-15), 1876-1882.
3. Rui Li, Xue Qiao, Qingyan Li, Rong He, Min Ye*, Cheng Xiang, Xionghao Lin, Dean Guo*. Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. B 2011, 879 (26), 2751-2758.
4. Xue Qiao, Min Ye*, De-lin Pan, Wen-juan Miao, Cheng Xiang, Jian Han, De-an Guo*. Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry. J. Chromatogr. A 2011, 1218, 107-117.
5. Xue Qiao, Xing Zhang, Min Ye*, Yan-fang Su, Jing Dong, Jian Han, Jun Yin, De-an Guo*. Rapid characterization of triterpene saponins from Conyza blinii by liquid chromatography coupled with mass spectrometry. Rapid Commun. Mass Spectrom. 2010, 24, 3340-3350.
6. Min Ye, Jian Han, Hubiao Chen, Junhua Zheng, Dean Guo. Analysis of phenolic compounds in rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 2007, 18(1), 82-91.
7. Min Ye, Yuning Yan, Dean Guo. Characterization of phenolic compounds in the Chinese herbal drug Tu-Si-Zi by liquid chromatography coupled to electrospray ionization mass spectrometry. Rapid Commun. Mass Spectrom. 2005, 19(11), 1469-1484.
8. Min Ye, Jian Han, Dongge An, Guangzhong Tu, Dean Guo. New cytotoxic bufadienolides from the biotransformation of resibufogenin by Mucor polymorphosporus. Tetrahedron 2005, 61(37), 8947-8955.
9. Min Ye, Jian Han, Guangzhong Tu, Dongge An, Dean Guo. Microbial hydroxylation of bufalin by Cunninghamella blakesleana and Mucor spinosus. J. Nat. Prod. 2005, 68(4), 626-628.
10. Min Ye, Guiqin Qu, Hongzhu Guo, Dean Guo. Specific 12b-hydroxylation of cinobufagin by filamentous fungi. Appl. Environ. Microbiol. 2004, 70(6), 3521-3527.
