Yanfang Yang

Lecturer

Research Areas

ADMET/Act. of traditional Chinese medicines

Education & Positions

University of Science and Technology of China (USTC), B.S., 1994

Massachusetts Institute of Technology, Ph.D., 2000

Beijing University of Chinese Medicine, Master, 1997-2000

Beijing Normal University, Doctor, 2008-2012

Peking University School of Pharmaceutical Sciences, 2000-

Research Interests

We study the absorption, distribution, metabolism, excretion, toxicity and activity of natural products from traditional Chinese medicines.

Publications

1. Yanfang Yang, Youbo Zhang, Zhijing Chen, Yingtao Zhang*, Xiuwei Yang*. Plasma pharmacokinetics and cerebral nuclei distribution of major constituents of Psoraleae Fructus in rats after oral administration. Phytomedicine 2018, 38: 166-174.

2. Yanfang Yang, Lei Zhang, Xiuwei Yang*. Distribution Assessments of Coumarins from Angelicae Pubescentis Radix in Rat Cerebrospinal Fluid and Brain by Liquid Chromatography Tandem Mass Spectrometry Analysis. Molecules 2018, 23(1), 225.

3. Yinan Zhang#, Yanfang Yang#, Xiuwei Yang*. Blood-brain barrier permeability and neuroprotective effects of three main alkaloids from Euodiae Fructus with MDCK-pHaMDR cell monolayer and PC12 cell line. Biomedicine & Pharmacotherapy 2018, 98: 82-87

4. Yanfang Yang, Qile Zhou, Xiuwei Yang*. Elucidation of Compatibility Interactions of Traditional Chinese Medicines: In Vitro Absorptions Across Caco-2 Monolayer of Coptidis Rhizoma and Euodiae Fructus in Zuojin and Fanzuojin Formulas as A Case. Phytotherapy Research 2017, 31(8): 1220-1229.

5. Yanfang Yang, Lei Zhang, Youbo Zhang, Xiuwei Yang*. Simultaneous assessment of absorption characteristics of coumarins from Angelicae Pubescentis Radix: in vitro transport across Caco-2 cell and in vivo pharmacokinetics in rats after oral administration. Journal of Chromatography B 2017, 1060: 308-315.