Xiu-Wei Yang   Professor

Research Areas

Natural Products Chemistry

Drug Metabolism

Education & Positions

University of Science and Technology of China (USTC), B.S., 1994

Massachusetts Institute of Technology, Ph.D., 2000

Peking University, Professor 1994-

Postdoctor, School of Pharmaceutical Sciences, Beijing Medical University, 1992-1994

Doctor, Toyama Medical and Pharmaceutical University, Japan, 1989-1992

Master, Toyama Medical and Pharmaceutical University, Japan, 1987-1989

Visiting Investigator, Toyama Medical and Pharmaceutical University, Japan, 1986

Assistant researcher, 1982-1986

Faculty Accolades

1. Most Cited Chinese Researchers (in Pharmacology, Toxiology & Pharmaceutics), Elsevier, 2014, 2015, 2016 & 2017

2. Second Prize of Natural Science Award, Scientific Research Outstanding Achievement Award of Higher Education, China Ministry of Education, 2013

3. Natural Science Award of the Ministry of Education of the People's Republic of China (First prize) in 2006

4. Chinese Medical Fund Award in 2001

5. Wu Jieping-Paul Jansen Medical Research Award (second prize) in 1995

Research Interests

Our research program spans a broad range of chemical biology, natural products chemistry, drug metabolism and biology.

Grants and fundings

1. The establishment of quality evaluation system of Chinese medicinal materials and demonstration study of their quality standard (Ministry of science and technology of People's Republic of China) (RMB 3,200,000)

2. The material basis study of the couplet medicine of Angelicae Dahuricae Radix–Chuanxiong Rhizoma (“Duliang Pill”) based on the processes of metabolism and disposition in intra-body, National Natural Science Foundation of China, 2015-2018 (RMB 1,000,000)

3. Fuke Qianjin tablet/capsule standardization construction, National Chinese Medicine Standardization Project, 2016-2018 (RMB 1,500,000)

Publications

1. Gui-Yun Cao, Xiu-Wei Yang*, Wei Xu, Fei Li. New inhibitors of nitric oxide production from the seeds of Myristica fragrans. Food and Chemical Toxicology, 2013, 62:167-171.

2. Fei Li, Xiu-Wei Yang*, Kristopher W. Krausz, Robert G. Nichols, Wei Xu, Andrew D. Patterson, and Frank J. Gonzalez*. Modulation of colon cancer by nutmeg. Journal of Proteome Research, 2015, 14 (4):1937-1946.

3. Hong-Ping Wang, You-Bo Zhang, Xiu-Wei Yang*, Da-Qing Zhao, Ying-Ping Wang. Rapid characterization of ginsenosides in the roots and rhizomes of Panax ginseng by UPLC？DAD？QTOF？MS/MS and simultaneous determination of 19 ginsenosides by HPLC-ESI-MS. Journal of Ginseng Research, 2016, 40(4):382-394.

4. Xiao-Jing Hu, You-Bo Zhang, Zi-Jing Zhao, Lei Zhang, Qi Wang*,Xiu-Wei Yang*. Metabolic detoxification of bakuchiol is mediated by oxidation of CYP 450s in liver microsomes. Food and Chemical Toxicology, 2018, 111, 385-392.

5. Qi-Le Zhou, Di-Na Zhu, Xiu-Wei Yang*, Wei Xu, Ying-Ping Wang. Development and validation of a UFLC–MS/MS method forsimultaneous quantification of sixty-six saponins and their sixaglycones: Application to comparative analysis of red ginseng andwhite ginseng. Journal of Pharmaceutical and Biomedical Analysis, 2018, 159, 153-165.