王弘:女,副教授,研究生导师
联系电话:010-82801559
电子邮箱:hw9505@bjmu.edu.cn
个人简历
1962年8月出生于北京市;1983年7月毕业于陕西中医药大学药学院,获学士学位;1983年8月~1994年12月在陕西省中药制药公司工作,任工程师和质量科长;1995年1月~1996年1月在日本富山医科药科大学和汉药研究所作客员研究员,从事天然药物研究;1996年2月至今在北京大学药学院学习和工作,获硕士学位,从事天然药物科研和教学工作;2002年任北京大学药学院副教授,2004年评为研究生导师。
研究领域
药用植物资源与新药研究;
中药活性成分与质量评价标准体系研究。
主要学术成果及获奖
长期从事药用植物、中药活性成分和质量标准等研究。先后承担国家教育部、国家“八五~十二五”攻关项目,国家发改委、中医药管理局、药典委等科研课题十余项;研究成果曾获国家科技进步二等奖1项、北京市科技进步三等奖1项;对银杏叶、松果菊、茜草、厚朴、金莲花、石韦、梅花、罗布麻、猪苓、枳实等多种中药的资源及质量标准进行了系统研究,其中药典质量标准研究项目中“茜草、梅花”的研究成果已收载于2015版、2010版《中国药典》一部;发表科研论文80余篇,其中SCI论文30篇,研究论文曾获中国药学会药物分析专业委员会评选的优秀论文一等奖2项、二等奖2项;科研成果申请和授权国家专利4项;新药研究成果获临床批件3项,通过卫生部功能食品审评2项;主编和参编著作6部;培养硕士研究生20余名,曾获北京大学医学部教学奖4项;担任《中国实验方剂学》杂志编委、2015年世界中医药学会联合会道地药材多维评价专业委员会委员、中国民族医药学会药用资源分会理事等职务。
近年发表的代表性论文
1. Yanqing Guan, Jing Dong , Shizhong Chen, Meixian Liu, DaidongWang, Xiaotian Zhang, HongWang*, Zongtao Lin*.Spectroscopic studies of the interaction mechanisms between mono-caffeoylquinic acids and transferrin. Spectrochimica Acta Part A Molecular & Biomolecular Spectroscopy .181 (2017) 82–90.
2. Hong Wang, Xiaotian Zhang, Daidong Wang, Hongyang Sun, Yuexiang Lan, Haixiu Jiang, Shizhong Chena*, Zongtao Lin*. An on-line analytical approach for detecting haptens inShuang-huang-lian powder injection. Journal of Chromatography A. 1513 (2017) 126–139.
3. Qingrong Fu, Cangman Zhang,Zongtao Lin , Hongyang Sun , Yi Liang , Haixiu Jiang , Zhiling Song , Hong Wang*, Shizhong Chen*. Rapid screening and identification of compounds with DNA-binding activity from Folium Citri Reticulatae using on-line HPLC–DAD–MSn coupled with a post column fluorescence detection system. Food Chemistry. 192 (2016) 250–259.
4. Meixian Liu,Jing Dong, Zongtao Lin, Yanyan Niu, Xiaotian Zhang, Haixiu Jiang,Ning Guo, Wei Li, Hong Wang*, Shizhong Chen*. Rapid screening of transferrin-binders in the flowers of Bauhinia blakeana Dunn by on-line high-performance liquid chromatography–diode-array detector–electrospray ionization–ion-trap–time-of - flight –mass spectrometry – transferrin–fluorescence detection system. Journal of Chromatography A. 1450 (2016) 17–28.
5. Yanyan Niu, Sensen Li, Zongtao Lin, Meixian Liu, Daidong Wang , Hong Wanga*,Shizhong Chena*. Development of propidium iodide as a fluorescence probe for theon-line screening of non-specific DNA-intercalators in Fufang Banbianlian Injection. Journal of Chromatography A. 1463 (2016) 102–109.
6. Sensen Li, Zongtao Lin, Haixiu Jiang, Lingkun Tong, Hong Wang*, Shizhong Chen*. Rapid Identification and Assignation of the Active Ingredients in Fufang Banbianlian Injection Using HPLC-DAD-ESI-IT-TOF-MS. Journal of Chromatographic Science. 2016, 1–13.
7. Cangman Zhang, Biao Ren, Zongtao Lin, Lingkun Tong, Hong Wang*, Shizhong Chen*. An analysis method for simultaneous screening of deoxyribonucleicacid-binding active compounds and investigating their mechanismsby ultra-fast liquid chromatography tandem mass spectrometrycoupled with fluorescence detection technology. Journal of Chromatography A. 1381 (2015) 160–172.
8. Xiaoxia Zhang, Zongtao Lin, Jinggui Fang, Meixian Liu, Yanyan Niu,Shizhong Chen?, Hong Wang?. An on-lin high-performance liquid chromatography–diode-arraydetector–electrospray ionization–ion-trap–time-of-flight–massspectrometry–total antioxidant capacity detection system applyingtwo antioxidant methods for activity evaluation of the edible flowersfrom Prunus mume. Journal of Chromatography A .1414 (2015) 88–102.
9. Hongyang Sun, Meixian Liu, Zongtao Lin, Haixiu Jiang, Yanyan Niu, Hong Wang*, hizhong Chen*. Comprehensive identification of 125 multifarious constituents inShuang–huang–lian powder injection by HPLC-DAD-ESI-IT-TOF-MS. Journal of Pharmaceutical and Biomedical Analysis. 115 (2015) 86–106.
10. Yi Liang, Gang Cui, Xiaoxue Wang, Wei Zhang, Quan An , Zongtao Lin, Hong Wang* , Shizhong Chen*. Pharmacokinetics of honokiol after intravenous guttae in beagle dogs assessed using ultra-performance liquid chromatography–tandem mass spectrometry. Biomedical chromatography . 2014, 28:1378-1383.
11. Biao Ren, Hong yang Sun, Hong Wang*. Simultaneous determination of seven caffeoylquinic acids and three Journal of Chinese armaceutical flavonoids in Pyrrosia petiolosa (Christ) Ching by RP-UFLC-DAD. Journal of Chinese armaceutical Sciences. 2014, 23 (9), 6 42–428.
12. Zhiling Song , Yuki Hashi, Hongyang Sun, Yi Liang, YuexiangLan, Hong Wang*,Shizhong Chen*. Simultaneous determination of 19 flavonoids in commercialtrollflowers by using high-performance liquid chromatographyand classification of samples by hierarchical clustering analysis. Fitoterapia . 91(11): 272–279.2013.
教学工作
主讲课程:
1.本科生课:《药用植物资源研究与进展》;《药用植物学》
2.研究生课:《药用植物化学分类学》;《天然药物研究进展》第一讲
编写教材:
1.全国高等学校药学专业规划教材 《药用植物学》 人民卫生出版社,北京,2016,编委.
2 .国家执业药师资格考试丛书-《中药学和中药药剂学》 北京大学医学出社,2007,主编.
3.国家职业药师资格考试全能强化题集-《中药学分册》,北京大学医学出版社,2007,编委.
4.北京大学药学教材 《药用植物学》 北京大学医学出版社,2004,编委.